Ortopedi

Ortopedins och handkirurgins sjukdomspanoramaRöntgenbild på ett knä

Ortopedin handlägger rörelseorganens skador och sjukdomar. Ortopediska skador uppstår genom trauma, vissa ortopediska sjukdomar är degenerativt betingade och ytterligare ett stort område är diagnostik, behandling och habilitering av medfödda tillstånd.

Ett trauma kan leda till frakturer och mjukdelsskador, och inom ortopedin behandlar vi bland annat livshotande skador som uppkommer vid trafikolyckor eller fall från hög höjd, ofta definierade som högenergiskador. Men ortopediskt trauma inkluderar även de betydligt vanligare fallolyckorna i samma plan, skador som företrädesvis drabbar barn och åldringar, och som ofta kallas lågenergisakador.

Ett stort område inom ortopedin utgörs av degenerativa sjukdomar som artros, alltså ledsvikt, samt mjukdelsrelaterade smärtor i nacke, rygg och extremiteter. Men även mer ovanliga tillstånd inom rörelseapparaten, som infektioner, tumörer och medfödda sjukdomar, kan kräva ortopedisk kompetens. Inflammatoriska ledsjukdomar, som reumatoid artrit kan också bli aktuella för ortopedisk behandling, och ortopedin utreder och behandlar även överbelastningsskador, ofta uppkomna som arbetsskador eller idrottsskador.

Förändring i det ortopediska sjukdomspanoramat

Ortopediska skador och sjukdomar drabbar alla åldersgrupper. Lågenergitrauma och degenerativa förändringar drabbar dock främst äldre individer. Då medellivslängden i Sverige har fördubblats de senaste 200 åren har andelen åldringar i samhället ökat. Tack vare en aktiv livsstil långt upp i åldrarna har vi idag också många fler skador och förslitningar som uppstått i samband med idrott eller annan fysisk aktivitet. Den förändrade samhällsdemografin och förändringar mot en mer aktiv livsstil har medfört en ökning av antalet individer med ortopediska åkommor, och denna trend förväntas öka.

Ortopedisk forskning

Historiskt sett har den ortopediska och handkirurgiska forskningen lett till fantastiska och mycket kännbara resultat för stora patientgrupper. Ta som exempel insättningen av konstgjorda leder, frakturkirurgin, eller replantationen av avskurna fingrar, behandlingar som för två generationer sedan tedde sig mer som ”science fiction”.

Målet med vår forskning är att ständigt förbättra diagnostik och behandling av patienter som drabbats av ovan nämnda skador och sjukdomar, och att systematiskt utvärdera nya behandlingsmetoder. Vår enhet bedriver forskning på många olika områden, alltifrån trauma och artros till barnortopedi och handkirurgi. Beroende på frågeställning använder vi vitt skilda metoder, från translationell forskning på odlade celler eller djur, via kliniska studier på patienter till storskalig epidemiologisk forskning på omfattande patientgrupper. 

På dessa sidor presenteras en överblick över de olika forskningsprojekten som pågår på enheten för ortopedi och handkirurgi. Glädjande nog är vi en väldigt aktiv enhet, med många aktiva doktorander och seniora forskargruppsledare, och vi har de senaste åren lyft fram många spännande forskningsresultat som delvis fått stor medial uppmärksamhet.


Nils Hailer, professor i ortopedi

Publikationer i DiVA 2018-2019, ortopedi

  • Eriksson, Thomas; Berg, Per; Olerud, Claes; Shalabi, Adel et al.

    Low-dose CT of postoperative pelvic fractures: a comparison with radiography

    Ingår i Acta Radiologica, s. 85-91, 2019.

  • Hailer, Yasmin; Penno, Eva

    Agreement of radiographic measurements and patient-reported outcome in 61 patients with Legg-Calvé-Perthes disease at mean follow-up of 28 years.

    Ingår i Journal of pediatric orthopedics. Part B, s. 100-106, 2019.

  • Yang, Yaohua; Wu, Lang; Shu, Xiang; Lu, Yingchang et al.

    Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

    Ingår i Cancer Research, s. 505-517, 2019.

  • Jiang, Xia; Finucane, Hilary K.; Schumacher, Fredrick R.; Schmit, Stephanie L. et al.

    Shared heritability and functional enrichment across six solid cancers

    Ingår i Nature Communications, 2019.

    Open access
  • Manabe, Nodoka; Covaro, Augusto; Bobinski, Lukas; Shimizu, Takachika et al.

    The Relationship between the Occipitocervical Junction and Thoracic Kyphosis in Ankylosing Spondylitis: A Retrospective Cohort Study of 86 Cervical Fractures in Surgically Treated Patients

    Ingår i Asian Spine Journal, s. 103-110, 2019.

    Open access
  • Lönne, Greger; Fritzell, Peter; Hägg, Olle; Nordvall, Dennis et al.

    Lumbar spinal stenosis: comparison of surgical practice variation and clinical outcome in three national spine registries

    Ingår i The spine journal, s. 41-49, 2019.

  • Huyghe, Jeroen R.; Bien, Stephanie A.; Harrison, Tabitha A.; Kang, Hyun Min et al.

    Discovery of common and rare genetic risk variants for colorectal cancer

    Ingår i Nature Genetics, s. 76-87, 2019.

  • Khalili, Hamed; Hakansson, Niclas; Chan, Simon S; Ludvigsson, Jonas F et al.

    No Association Between Consumption of Sweetened Beverages and Risk of Later-Onset Crohn's Disease or Ulcerative Colitis.

    Ingår i Clinical Gastroenterology and Hepatology, s. 123-129, 2019.

  • Kaluza, J; Håkansson, N; Harris, H R; Orsini, N et al.

    Influence of anti-inflammatory diet and smoking on mortality and survival in men and women: two prospective cohort studies.

    Ingår i Journal of Internal Medicine, s. 75-91, 2019.

  • Björk, Anne; Ribom, Eva; Johansson, Gunnar; Scragg, R. et al.

    Variations in the vitamin D receptor gene are not associated with measures of muscle strength, physical performance, or falls in elderly men: Data from MrOS Sweden

    Ingår i Journal of Steroid Biochemistry and Molecular Biology, s. 160-165, 2019.

  • Larsson, Susanna C.; Drca, Nikola; Michaëlsson, Karl

    Serum Magnesium and Calcium Levels and Risk of Atrial Fibrillation: A Mendelian Randomization Study

    Ingår i CIRCULATION: GENOMIC AND PRECISION MEDICINE, 2019.

  • MacDowall, Anna; Skeppholm, Martin; Lindhagen, Lars; Robinson, Yohan et al.

    Artificial Disc Replacement versus Fusion in Patients with Cervical Degenerative Disc Disease with radiculopathy: 5-year Outcomes from the National Swedish Spine Register

    Ingår i Journal of Neurosurgery, s. 159-167, 2019.

  • MacDowall, Anna; Canto Moreira, Nuno; Marques, Catarina; Skeppholm, Martin et al.

    Artificial disc replacement versus fusion in patients with cervical degenerative disc disease and radiculopathy: a randomized controlled trial with 5-year outcomes

    Ingår i Journal of Neurosurgery, s. 323-331, 2019.

  • Karasik, David; Zillikens, M. Carola; Hsu, Yi-Hsiang; Aghdassi, Ali et al.

    Disentangling the genetics of lean mass

    Ingår i American Journal of Clinical Nutrition, s. 276-287, 2019.

  • Ludvigsson, Jonas F.; Mahl, Martin; Sachs, Michael C.; Björk, Jan et al.

    Fracture Risk in Patients With Inflammatory Bowel Disease: A Nationwide Population-Based Cohort Study From 1964 to 2014

    Ingår i American Journal of Gastroenterology, s. 291-304, 2019.

  • Cronholm, Felix; Rosengren, Björn E.; Nilsson, Jan-Åke; Ohlsson, Claes et al.

    The fracture predictive ability of a musculoskeletal composite score in old men - data from the MrOs Sweden study

    Ingår i BMC Geriatrics, 2019.

    Open access
  • Kaluza, Joanna; Harris, Holly; Linden, Anders; Wolk, Alicja et al.

    Long-term unprocessed and processed red meat consumption and risk of chronic obstructive pulmonary disease: a prospective cohort study of women

    Ingår i European Journal of Nutrition, s. 665-672, 2019.

    Open access
  • Larsson, Susanna C; Wolk, Alicja; Bäck, Magnus

    Dietary patterns, food groups, and incidence of aortic valve stenosis: A prospective cohort study.

    Ingår i International Journal of Cardiology, s. 184-188, 2019.

    Open access
  • Borg, Tomas; Hernefalk, Björn; Hailer, Nils P.

    Acute total hip arthroplasty combined with internal fixation for displaced acetabular fractures in the elderly: A short-term comparison with internal fixation alone after a minimum of two years

    Ingår i The Bone & Joint Journal, s. 478-483, 2019.

  • Larsson, Susanna C.; Flicker, Leon

    Vitamin D: A novel protective factor for delirium?

    Ingår i Neurology, s. 553-554, 2019.

  • Larsson, Susanna C.; Traylor, Matthew; Markus, Hugh S.

    Homocysteine and small vessel stroke: A mendelian randomization analysis

    Ingår i Annals of Neurology, s. 495-501, 2019.

    Open access
  • Wang, Mo; Mittendorfer-Rutz, Ellenor; Dorner, Thomas E.; Pazarlis, Konstantinos A. et al.

    Determinants of work disability following lumbar spine decompression surgery

    Ingår i Scandinavian Journal of Public Health, s. 281-292, 2019.

  • Bien, Stephanie A.; Su, Yu-Ru; Conti, David V.; Harrison, Tabitha A. et al.

    Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

    Ingår i Human Genetics, s. 307-326, 2019.

    Open access
  • Larsson, Susanna C.; Allara, Elias; Mason, Amy M.; Michaëlsson, Karl et al.

    Thyroid Function and Dysfunction in Relation to 16 Cardiovascular Diseases: A Mendelian Randomization Study

    Ingår i Circulation: Genomic and Precision Medicine, s. 121 121-126 126, 2019.

    Open access
  • Larsson, Susanna C.; Traylor, Matthew; Burgess, Stephen; Boncoraglio, Giorgio B. et al.

    Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

    Ingår i Neurology, s. E944-E950, 2019.

    Open access
  • Larsson, Susanna C.; Drca, Nikola; Mason, Amy M.; Burgess, Stephen et al.

    Resting Heart Rate and Cardiovascular Disease Mendelian Randomization Analysis

    Ingår i CIRCULATION-GENOMIC AND PRECISION MEDICINE, s. 127 127-129 129, 2019.

  • Larsson, Susanna C.; Wolk, Alicja

    Sedentary leisure-time in relation to mortality and survival time

    Ingår i Journal of Science and Medicine in Sport, s. 562-567, 2019.

  • Lind, Lars; Kullberg, Joel; Ahlström, Håkan; Michaëlsson, Karl et al.

    Proof of principle study of a detailed whole-body image analysis technique, "Imiomics", regarding adipose and lean tissue distribution

    Ingår i Scientific Reports, 2019.

    Open access
  • Law, Philip J.; Timofeeva, Maria; Fernandez-Rozadilla, Ceres; Timofeeva, Aria et al.

    Association analyses identify 31 new risk loci for colorectal cancer susceptibility

    Ingår i Nature Communications, 2019.

    Open access
  • Hulsart Billström, Gry; Janson, Oscar; Engqvist, Håkan; Welch, Ken et al.

    Thromboinflammation as bioactivity assessment of H2O2-alkali modified titanium surfaces

    Ingår i Journal of materials science. Materials in medicine, 2019.

    Open access
  • Kharazmi, Mohammad; Michaëlsson, Karl; Schilcher, Jorg; Eriksson, Niclas et al.

    A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral Fracture

    Ingår i Calcified Tissue International, s. 51-67, 2019.

    Open access
  • Weiss, Rudiger J.; Karrholm, Johan; Rolfson, Ola; Hailer, Nils P. et al.

    Increased early mortality and morbidity after total hip arthroplasty in patients with socioeconomic disadvantage: a report from the Swedish Hip Arthroplasty Register

    Ingår i Acta Orthopaedica, s. 264-269, 2019.

    Open access
  • Cnudde, Peter; Bulow, Erik; Nemes, Szilard; Tyson, Yosef et al.

    Association between patient survival following reoperation after total hip replacement and the reason for reoperation: an analysis of 9,926 patients in the Swedish Hip Arthroplasty Register

    Ingår i Acta Orthopaedica, s. 226-230, 2019.

    Open access
  • Kaluza, Joanna; Harris, Holly; Melhus, Håkan; Michaëlsson, Karl et al.

    Questionnaire-Based Anti-Inflammatory Diet Index as a Predictor of Low-Grade Systemic Inflammation.

    Ingår i Antioxidants and Redox Signaling, s. 78-84, 2018.

  • Jiang, Xia; O'Reilly, Paul F.; Aschard, Hugues; Hsu, Yi-Hsiang et al.

    Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

    Ingår i Nature Communications, 2018.

  • Praud, Delphine; Rota, Matteo; Pelucchi, Claudio; Bertuccio, Paola et al.

    Cigarette smoking and gastric cancer in the Stomach Cancer Pooling (StoP) Project.

    Ingår i European Journal of Cancer Prevention, s. 124-133, 2018.

  • Ordóñez-Mena, J M; Walter, V; Schöttker, B; Jenab, M et al.

    Impact of prediagnostic smoking and smoking cessation on colorectal cancer prognosis: a meta-analysis of individual patient data from cohorts within the CHANCES consortium.

    Ingår i Annals of Oncology, s. 472-483, 2018.

  • Nordenvall, Caroline; Oskarsson, Viktor; Wolk, Alicja

    Fruit and vegetable consumption and risk of cholecystectomy: a prospective cohort study of women and men.

    Ingår i European Journal of Nutrition, s. 75-81, 2018.

  • Lourdudoss, Cecilia; Di Giuseppe, Daniela; Wolk, Alicja; Westerlind, Helga et al.

    Dietary Intake of Polyunsaturated Fatty Acids and Pain in Spite of Inflammatory Control Among Methotrexate-Treated Early Rheumatoid Arthritis Patients.

    Ingår i Arthritis care & research, s. 205-212, 2018.

  • Aspenberg, Per; Michaëlsson, Karl; Rydholm, Anders; Svensson, Olle et al.

    Artrosskolan: evidensen måste stärkas

    Ingår i Läkartidningen, 2018.

  • Gunnesalen, Ing 10, Psykiatrins hus, Sjukhusvägen, Uppsala 2018-01-12 kl 09:00

    Robinson, Anna-Lena

    Axis Fractures in Elderly: Epidemiology and Treatment related outcome

    Open access
  • Larsson, Susanna C; Drca, Nikola; Jensen-Urstad, Mats; Wolk, Alicja et al.

    Chocolate consumption and risk of atrial fibrillation: Two cohort studies and a meta-analysis

    Ingår i American Heart Journal, s. 86-90, 2018.

  • Kaluza, Joanna; Harris, Holly; Wallin, Alice; Linden, Anders et al.

    Dietary Fiber Intake and Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men.

    Ingår i Epidemiology, s. 254-260, 2018.

  • Atesok, Kivanc; Tanaka, Nobuhiro; O'Brien, Andrew; Robinson, Yohan et al.

    Posttraumatic Spinal Cord Injury without Radiographic Abnormality

    Ingår i Advances in Orthopedics, 2018.

    Open access
  • Cornelis, M C; Gustafsson, Stefan; Ärnlöv, J; Elmståhl, S et al.

    Targeted proteomic analysis of habitual coffee consumption.

    Ingår i Journal of Internal Medicine, s. 200-211, 2018.

  • Yan, Hongji; Casalini, Tommaso; Hulsart Billström, Gry; Wang, Shujiang et al.

    Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation

    Ingår i Biomaterials, s. 190-202, 2018.

  • Bjornsdottir, Sigrun Vala; Triebel, Jan; Arnljotsdottir, Margret; Tomasson, Gunnar et al.

    Long-lasting improvements in health-related quality of life among women with chronic pain, following multidisciplinary rehabilitation

    Ingår i Disability and Rehabilitation, s. 1764-1772, 2018.

  • Hailer, Yasmin; Hailer, Nils P.

    Is Legg-Calve-Perthes Disease a Local Manifestation of a Systemic Condition?

    Ingår i Clinical Orthopaedics and Related Research, s. 1055-1064, 2018.

  • Brüggemann, Anders; Mallmin, Hans; Hailer, Nils P

    Do dual-mobility cups cemented into porous tantalum shells reduce the risk of dislocation after revision surgery?: A retrospective cohort study on 184 patients

    Ingår i Acta Orthopaedica, s. 156-162, 2018.

    Open access
  • Christersson, Albert; Larsson, Sune; Sandén, Bengt

    Clinical outcome after plaster cast fixation for 10 days versus 1 month in reduced distal radius fractures: A prospective randomized study

    Ingår i Scandinavian Journal of Surgery, s. 82-90, 2018.

  • Larsson, Susanna C.; Wallin, Alice; Håkansson, Niclas; Stackelberg, Otto et al.

    Type 1 and type 2 diabetes mellitus and incidence of seven cardiovascular diseases

    Ingår i International Journal of Cardiology, s. 66-70, 2018.

    Open access
  • Larsson, Susanna C; Melhus, Håkan; Michaëlsson, Karl

    Circulating Serum 25-Hydroxyvitamin D Levels and Bone Mineral Density: Mendelian Randomization Study

    Ingår i Journal of Bone and Mineral Research, s. 840-844, 2018.

  • Schizas, Nikos; König, Niclas; Andersson, Brittmarie; Vasylovska, Svitlana et al.

    Neural crest stem cells protect spinal cord neurons from excitotoxic damage and inhibit glial activation by secretion of brain-derived neurotrophic factor

    Ingår i Cell and Tissue Research, s. 493-505, 2018.

    Open access
  • Larsson, Susanna C.; Burgess, Stephen; Michaëlsson, Karl

    Serum magnesium levels and risk of coronary artery disease: Mendelian randomisation study

    Ingår i BMC Medicine, 2018.

    Open access
  • Ferro, Ana; Morais, Samantha; Rota, Matteo; Pelucchi, Claudio et al.

    Alcohol intake and gastric cancer: Meta-analyses of published data versus individual participant data pooled analyses (StoP Project)

    Ingår i Cancer Epidemiology, s. 125-132, 2018.

  • Hailer, Nils

    20 years of porous tantalum in primary and revision hip arthroplasty-time for a critical appraisal

    Ingår i Acta Orthopaedica, s. 254-255, 2018.

  • Bjelland, E. K.; Hofvind, S.; Byberg, Liisa; Eskild, A. et al.

    The relation of age at menarche with age at natural menopause: A population study of 336 788 women in Norway

    Ingår i British Journal of Obstetrics and Gynecology, s. 40-40, 2018.

  • Michaëlsson, Karl; Wolk, Alicja; Warensjö, Eva; Melhus, Håkan et al.

    Intake of milk or fermented milk combined with fruit and vegetable consumption in relation to hip fracture rates: A cohort study of Swedish women.

    Ingår i Journal of Bone and Mineral Research, s. 449-457, 2018.

  • Zhou, Ang; Taylor, Amy E.; Karhunen, Ville; Zhan, Yiqiang et al.

    Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants

    Ingår i Scientific Reports, 2018.

    Open access
  • Neumeyer, Sonja; Banbury, Barbara L.; Arndt, Volker; Berndt, Sonja I. et al.

    Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer

    Ingår i British Journal of Cancer, s. 1639-1647, 2018.

  • Larsson, S. C.; Wolk, Alicja; Håkansson, N.; Bäck, M. et al.

    Coffee consumption and risk of aortic valve stenosis: A prospective study

    Ingår i NMCD. Nutrition Metabolism and Cardiovascular Diseases, s. 803-807, 2018.

  • Elmekaty, Mohamed; ElMehy, Emad; Försth, Peter; MacDowall, Anna et al.

    Safety of a novel modular cage for transforaminal lumbar interbody fusion: clinical cohort study in 20 patients with degenerative disc disease

    Ingår i SICOT-J, 2018.

    Open access
  • Canova, Cristina; Pitter, Gisella; Zanier, Loris; Simonato, Lorenzo et al.

    Risk of Fractures in Youths with Celiac Disease-A Population-Based Study

    Ingår i Journal of Pediatric Surgery Case Reports, s. 117-120, 2018.

  • Ohlsson, Claes; Nethander, Maria; Karlsson, Magnus K.; Rosengren, Bjorn E. et al.

    Serum DHEA and Its Sulfate Are Associated With Incident Fall Risk in Older Men: The MrOS Sweden Study

    Ingår i Journal of Bone and Mineral Research, s. 1227-1232, 2018.

  • Larsson, Sune

    Clavicula fractures: considerations when plating

    Ingår i Injury, s. S24-S28, 2018.

  • Benetou, V.; Orfanos, P.; Feskanich, D.; Michaëlsson, Karl et al.

    Mediterranean diet and hip fracture incidence among older adults: the CHANCES project

    Ingår i Osteoporosis International, s. 1591-1599, 2018.

  • Schumacher, Fredrick R.; Al Olama, Ali Amin; Berndt, Sonja I.; Benlloch, Sara et al.

    Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Ingår i Nature Genetics, s. 928-936, 2018.

  • Cnudde, Peter; Rolfson, Ola; Timperley, A. John; Garland, Anne et al.

    Do Patients Live Longer After THA and Is the Relative Survival Diagnosis-specific?

    Ingår i Clinical Orthopaedics and Related Research, s. 1166-1175, 2018.

  • Christersson, Albert; Larsson, Sune; Sörensen, Jens

    Presurgical localization of infected avascular bone segments in chronic complicated posttraumatic osteomyelitis in the lower extremity using dual-tracer PET/CT.

    Ingår i EJNMMI Research, 2018.

    Open access
  • Hulsart Billström, Gry; Selvaraju, Ramkumar; Estrada, Sergio; Lubberink, Mark et al.

    Non-invasive tri-modal visualisation via PET/SPECT/μCT of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration: A proof of concept

    Ingår i Journal of Controlled Release, s. 178-186, 2018.

    Open access
  • Dorner, Thomas E.; Helgesson, Magnus; Nilsson, Kerstin; Pazarlis, Konstantinos A. et al.

    Course and characteristics of work disability 3 years before and after lumbar spine decompression surgery: a national population-based study

    Ingår i Scientific Reports, 2018.

    Open access
  • Robinson, Anna-Lena; Schmeiser, Gregor; Robinson, Yohan; Olerud, Claes et al.

    Surgical vs. non-surgical management of displaced type-2 odontoid fractures in patients aged 75 years and older: study protocol for a randomised controlled trial

    Ingår i Trials, 2018.

    Open access
  • Sarajlic, Philip; Wolk, Alicja; Bäck, Magnus; Larsson, Susanna C. et al.

    Physical Activity Does Not Reduce Aortic Valve Stenosis Incidence

    Ingår i Circulation Journal, s. 2372-2374, 2018.

  • Moraeus, Lotta; Warensjö Lemming, Eva; Hursti, Ulla-Kaisa Koivisto; Arnemo, Marianne et al.

    Riksmaten Adolescents 2016-17: A national dietary survey in Sweden - design, methods, and participation

    Ingår i Food & Nutrition Research, 2018.

    Open access
  • Elmekaty, Mohamed; Kotani, Yoshihisa; El Mehy, Emad; Robinson, Yohan et al.

    Clinical and Radiological Comparison between Three Different Minimally Invasive Surgical Fusion Techniques for Single-Level Lumbar Isthmic and Degenerative Spondylolisthesis: Minimally Invasive Surgical Posterolateral Fusion versus Minimally Invasive Surgical Transforaminal Lumbar Interbody Fusion versus Midline Lumbar Fusion

    Ingår i Asian Spine Journal, s. 870-879, 2018.

    Open access
  • Augat, Peter; Larsson, Sune

    Plating of fractures: current treatments and complications

    Ingår i Injury, s. S1-S1, 2018.

  • Khalili, Hamed; Wolk, Alicja

    Reply to: The Association Between Consumption of Sweetened Beverages and the Risk of Inflammatory Bowel Disease

    Ingår i Clinical Gastroenterology and Hepatology, s. 1682-1682, 2018.

  • Eriksson, Hannah K.; Nordström, Jakob; Gabrysch, Katja; Hailer, Nils P. et al.

    Does the Alpha-defensin Immunoassay or the Lateral Flow Test Have Better Diagnostic Value for Periprosthetic Joint Infection?: A Systematic Review

    Ingår i Clinical Orthopaedics and Related Research, s. 1065-1072, 2018.

  • Stilling, Frej; Wolk, Alicja; Religa, Dorota; Leppert, Jerzy et al.

    Adipose tissue fatty acid composition and cognitive impairment

    Ingår i Nutrition (Burbank, Los Angeles County, Calif.), s. 153-157, 2018.

  • MacDowall, Anna; Skeppholm, Martin; Lindhagen, Lars; Robinson, Yohan et al.

    Effects of preoperative mental distress versus surgical modality, arthroplasty, or fusion on long-term outcome in patients with cervical radiculopathy

    Ingår i Journal of Neurosurgery, s. 371-379, 2018.

  • Försth, Peter; Svedniark, Per; Noz, Marilyn E.; Maguire Jr, Gerald Q. et al.

    Motion Analysis in Lumbar Spinal Stenosis With Degenerative Spondylolisthesis A Feasibility Study of the 3DCT Technique Comparing Laminectomy Versus Bilateral Laminotomy

    Ingår i CLINICAL SPINE SURGERY, s. E397 E397-E402 E402, 2018.

  • Michaëlsson, Karl; Byberg, Liisa

    Interpretation of milk research results

    Ingår i Osteoporosis International, s. 773-775, 2018.

  • Mei, Xueshuang; Atturo, Francesca; Wadin, Karin; Larsson, Sune et al.

    Human inner ear blood supply revisited: the Uppsala collection of temporal bone - an international resource of education and collaboration

    Ingår i Upsala Journal of Medical Sciences, s. 131-142, 2018.

    Open access
  • Grip, Olivia; Wanhainen, Anders; Michaëlsson, Karl; Lindhagen, Lars et al.

    Open versus endovascular revascularization in the treatment of acute lower limb ischaemia

    Ingår i British Journal of Surgery, s. 1598-1606, 2018.

    Open access
  • Robinson, Anna-Lena; Olerud, Claes; Robinson, Yohan

    Surgical treatment improves survival of elderly with axis fracture: a national population-based multi-registry cohort study

    Ingår i The spine journal, s. 1853-1860, 2018.

    Open access
  • Warensjö Lemming, Eva; Liisa, Byberg; Wolk, Alicja; Michaëlsson, Karl et al.

    A comparison between two healthy diet scores, the modified Mediterranean diet score and the Healthy Nordic Food Index, in relation to all-cause and cause-specific mortality

    Ingår i British Journal of Nutrition, s. 836-846, 2018.

    Open access
  • Schart-Moren, Nadine; Larsson, Sune; Rask-Andersen, Helge; Li, Hao et al.

    Three-Dimensional Analysis of the Fundus of the Human Internal Acoustic Canal

    Ingår i Ear and Hearing, s. 563-572, 2018.

  • Stattin, Karl; Hållmarker, Ulf; Ärnlöv, Johan; James, Stefan et al.

    Decreased Hip, Lower Leg, and Humeral Fractures but Increased Forearm Fractures in Highly Active Individuals

    Ingår i Journal of Bone and Mineral Research, s. 1842-1850, 2018.

  • Farvid, Maryam S; Stern, Mariana C; Norat, Teresa; Sasazuki, Shizuka et al.

    Consumption of red and processed meat and breast cancer incidence: A systematic review and meta-analysis of prospective studies.

    Ingår i International Journal of Cancer, s. 2787-2799, 2018.

    Open access
  • Mahmood, Mahmood W; Abraham-Nordling, Mirna; Håkansson, Niclas; Wolk, Alicja et al.

    High intake of dietary fibre from fruit and vegetables reduces the risk of hospitalisation for diverticular disease.

    Ingår i European Journal of Nutrition, 2018.

    Open access
  • Larsson, Susanna C; Traylor, Matthew; Markus, Hugh S; Michaëlsson, Karl et al.

    Serum Parathyroid Hormone, 25-Hydroxyvitamin D, and Risk of Alzheimer's Disease: A Mendelian Randomization Study

    Ingår i Nutrients, 2018.

    Open access
  • Hirasawa, Atsuhiko; Robinson, Yohan; Olerud, Claes; Wakao, Norimitsu et al.

    Regional Differences in Diffuse Idiopathic Skeletal Hyperostosis: A Retrospective Cohort Study from Sweden and Japan

    Ingår i Spine, s. E1474-E1478, 2018.

  • Dadaev, Tokhir; Saunders, Edward J; Newcombe, Paul J; Anokian, Ezequiel et al.

    Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

    Ingår i Nature Communications, 2018.

    Open access
  • Machiela, Mitchell J; Hofmann, Jonathan N; Carreras-Torres, Robert; Brown, Kevin M et al.

    Corrigendum re "Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma": [Eur Urol 2017;72:747-54

    Ingår i European Urology, s. e85-e86, 2018.

  • Larsson, Susanna C; Wolk, Alicja

    The Role of Lifestyle Factors and Sleep Duration for Late-Onset Dementia: A Cohort Study

    Ingår i Journal of Alzheimer's Disease, s. 579-586, 2018.

    Open access
  • Schoemaker, Minouk J; Nichols, Hazel B; Wright, Lauren B; Brook, Mark N et al.

    Association of Body Mass Index and Age With Subsequent Breast Cancer Risk in Premenopausal Women.

    Ingår i JAMA Oncology, 2018.

  • Adams, Charleen; Richmond, Rebecca C; Santos Ferreira, Diana L; Spiller, Wes et al.

    Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study.

    Ingår i Cancer Epidemiology, Biomarkers and Prevention, 2018.

  • Petimar, J; O'Reilly, É; Adami, H-O; van den Brandt, P A et al.

    Coffee, tea, and caffeine intake and amyotrophic lateral sclerosis mortality in a pooled analysis of eight prospective cohort studies.

    Ingår i European Journal of Neurology, 2018.

    Open access
  • MacDowall, Anna; Skeppholm, Martin; Robinson, Yohan; Olerud, Claes et al.

    Validation of the Visual Analogue Scale in the Cervical Spine

    Ingår i Journal of Eurosurgery, s. 227-235, 2018.

  • Crippa, Alessio; Larsson, Susanna C; Discacciati, Andrea; Wolk, Alicja et al.

    Red and processed meat consumption and risk of bladder cancer: a dose-response meta-analysis of epidemiological studies.

    Ingår i European Journal of Nutrition, s. 689-701, 2018.

    Open access
  • O'Mara, Tracy A; Glubb, Dylan M; Amant, Frederic; Annibali, Daniela et al.

    Identification of nine new susceptibility loci for endometrial cancer.

    Ingår i Nature Communications, 2018.

    Open access
  • Schmit, Stephanie L; Edlund, Christopher K; Schumacher, Fredrick R; Gong, Jian et al.

    Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

    Ingår i Journal of the National Cancer Institute, 2018.

  • Lindblad, Birgitta Ejdervik; Håkansson, Niclas; Wolk, Alicja

    Metabolic syndrome and some of its components in relation to risk of cataract extraction.: A prospective cohort study of men

    Ingår i Acta Ophthalmologica, 2018.

    Open access
  • Lourdudoss, Cecilia; Arnaud, Laurent; Wolk, Alicja; van Vollenhoven, Ronald F et al.

    Long-Term Dietary Changes after Diagnosis of Rheumatoid Arthritis in Swedish Women: Data from a Population-Based Cohort

    Ingår i International Journal of Rheumatology, 2018.

    Open access
  • Gaudet, Mia M; Gierach, Gretchen L; Carter, Brian D; Luo, Juhua et al.

    Pooled Analysis of Nine Cohorts Reveals Breast Cancer Risk Factors by Tumor Molecular Subtype.

    Ingår i Cancer Research, s. 6011-6021, 2018.

  • O'Reilly, Éilis J; Wang, Molin; Adami, Hans-Olov; Alonso, Alvaro et al.

    Prediagnostic body size and risk of amyotrophic lateral sclerosis death in 10 studies

    Ingår i Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, s. 396-406, 2018.

    Open access
  • Michaëlsson, Karl; Melhus, Håkan; Larsson, Susanna C.

    Serum 25-Hydroxyvitamin D Concentrations and Major Depression: A Mendelian Randomization Study

    Ingår i Nutrients, 2018.

    Open access
  • Wang, Xiaoliang; Dai, James Y; Albanes, Demetrius; Arndt, Volker et al.

    Mendelian randomization analysis of C-reactive protein on colorectal cancer risk

    Ingår i International Journal of Epidemiology, 2018.

  • Atturo, Francesca; Schart-Moren, Nadine; Larsson, Sune; Rask-Andersen, Helge et al.

    The Human Cochlear Aqueduct and Accessory Canals: a Micro-CT Analysis Using a 3D Reconstruction Paradigm

    Ingår i Otology and Neurotology, s. e429-e435, 2018.

  • Ferro, Ana; Morais, Samantha; Rota, Matteo; Pelucchi, Claudio et al.

    Tobacco smoking and gastric cancer:: meta-analyses of published data versus pooled analyses of individual participant data (StoP Project).

    Ingår i European Journal of Cancer Prevention, s. 197-204, 2018.

  • Hållmarker, Ulf; Lindbäck, Johan; Michaëlsson, Karl; Ärnlöv, Johan et al.

    Survival and incidence of cardiovascular diseases in participants in a long-distance ski race (Vasaloppet, Sweden) compared to the background population

    Ingår i European Heart Journal - Quality of Care and Clinical Outcomes, s. 91-97, 2018.

  • Procter, Philip; Pujari-Palmer, Michael; Hulsart Billström, Gry; Insley, Gerard et al.

    A new ex-vivo murine model for evaluation of adhesiveness of a novel biomimetic bone glue

    2018.

  • Procter, Philip; Pujari-Palmer, Michael; Hulsart Billström, Gry; Larsson, Sune et al.

    Designing A Commercial Biomaterial For A Specific Unmet Clinical Need –: An Adhesive Odyssey

    2018.

  • Tsikandylakis, Georgios; Kärrholm, Johan; Hailer, Nils P.; Eskelinen, Antti et al.

    No Increase in Survival for 36-mm versus 32-mm Femoral Heads in Metal-on-polyethylene THA: A Registry Study

    Ingår i Clinical Orthopaedics and Related Research, s. 2367-2378, 2018.

  • Rysinska, Agata; Skoldenberg, Olof; Garland, Anne; Rolfson, Ola et al.

    Aseptic loosening after total hip arthroplasty and the risk of cardiovascular disease: A nested case-control study

    Ingår i PLoS ONE, 2018.

    Open access
  • Harvey, Nicholas C.; Oden, Anders; Orwoll, Eric; Lapidus, Jodi et al.

    Measures of Physical Performance and Muscle Strength as Predictors of Fracture Risk Independent of FRAX, Falls, and aBMD: A Meta-Analysis Of The Osteoporotic Fractures In Men (MrOS) Study

    Ingår i Journal of Bone and Mineral Research, s. 2150-2157, 2018.

    Open access
  • Harvey, Nicholas; Oden, Anders; Orwoll, Eric; Kwok, Timothy et al.

    Definitions of sarcopenia as predictors of fracture risk independent of FRAX, falls and BMD: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study

    Ingår i Journal of Bone and Mineral Research, s. 13-14, 2018.

  • Vandenput, Liesbeth; Nethander, Maria; Karlsson, Magnus; Rosengren, Bjorn et al.

    Serum DHEA and its Sulfate Are Associated with Incident Fall Risk in Older Men - the MrOS Sweden Study

    Ingår i Journal of Bone and Mineral Research, s. 310-310, 2018.

  • Björk, Anne; Mellström, Dan; Ohlsson, Claes; Karlsson, Magnus et al.

    Haplotypes in the CYP2R1 gene are associated with levels of 25(OH)D and bone mineral density, but not with other markers of bone metabolism (MrOS Sweden)

    Ingår i PLoS ONE, 2018.

    Open access
  • Laszkowska, M.; Mahadev, S.; Sundström, Johan; Lebwohl, B. et al.

    Systematic review with meta-analysis: the prevalence of coeliac disease in patients with osteoporosis

    Ingår i Alimentary Pharmacology and Therapeutics, s. 590-597, 2018.

  • Robinson, Yohan; Lison Almkvist, Viktor; Fahlstedt, Madelen; Olerud, Claes et al.

    Finite element analysis of long posterior transpedicular instrumentation for cervicothoracic fractures related to ankylosing spondylitis

    Ingår i Global Spine Journal, s. 570-578, 2018.

    Open access
  • Larsson, Susanna C.; Burgess, Stephen; Michaëlsson, Karl

    Genetic association between adiposity and gout: a Mendelian randomization study

    Ingår i Rheumatology, s. 2145-2148, 2018.

  • Mitchell, Adam; Fall, Tove; Melhus, Håkan; Wolk, Alicja et al.

    Type 2 Diabetes in Relation to Hip Bone Density, Area, and Bone Turnover in Swedish Men and Women: A Cross-Sectional Study

    Ingår i Calcified Tissue International, s. 501-511, 2018.

    Open access
  • Wu, Lang; Shi, Wei; Long, Jirong; Guo, Xingyi et al.

    A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.

    Ingår i Nature Genetics, s. 968-978, 2018.

  • Trabert, Britton; Poole, Elizabeth M; White, Emily; Visvanathan, Kala et al.

    Analgesic Use and Ovarian Cancer Risk: An Analysis in the Ovarian Cancer Cohort Consortium.

    Ingår i Journal of the National Cancer Institute, 2018.

  • Wu, Huaxing; Mhd Omar, Nor Adila; Håkansson, Niclas; Wolk, Alicja et al.

    Evaluation of alkylresorcinols in adipose tissue biopsies as a long-term biomarker of whole-grain wheat and rye intake in free-living Swedish men and women.

    Ingår i Public Health Nutrition, s. 1933-1942, 2018.

  • Lu, Yingchang; Beeghly-Fadiel, Alicia; Wu, Lang; Guo, Xingyi et al.

    A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.

    Ingår i Cancer Research, s. 5419-5430, 2018.

  • Kaluza, Joanna; Harris, Holly R; Linden, Anders; Wolk, Alicja et al.

    Long-term consumption of fruits and vegetables and risk of chronic obstructive pulmonary disease: a prospective cohort study of women

    Ingår i International Journal of Epidemiology, s. 1897-1909, 2018.

  • Byberg, Liisa; Michaëlsson, Karl

    Milk and other dairy foods and risk of hip fracture in men and women: Comments on Feskanich et al.

    Ingår i Osteoporosis International, s. 1221-1222, 2018.

  • Stenemo, Markus; Nowak, Christoph; Byberg, Liisa; Sundström, Johan et al.

    Circulating proteins as predictors of incident heart failure in the elderly

    Ingår i European Journal of Heart Failure, s. 55-62, 2018.

    Open access
  • Lindahl, Katarina; Astrom, Eva; Dragomir, Anca; Symoens, Sofie et al.

    Homozygosity for CREB3L1 premature stop codon in first case of recessive osteogenesis imperfecta associated with OASIS-deficiency to survive infancy

    Ingår i Bone, s. 268-277, 2018.

  • Koller, Heiko; Ames, Christopher; Mehdian, Hossein; Bartels, Ronald et al.

    Characteristics of deformity surgery in patients with severe and rigid cervical kyphosis (CK): results of the CSRS-Europe multi-centre study project.

    Ingår i European spine journal, s. 324-344, 2018.

    Open access
  • Ullmark, Gösta; Sörensen, Jens; Maripuu, Enn; Nilsson, Olle et al.

    Fingerprint pattern of bone mineralisation on cemented and uncemented femoral stems: analysis by [18F]-fluoride-PET in a randomised clinical trial

    Ingår i HIP International, 2018.