Urology

Research in urological cancer

Urological cancer is increasing in number. The available diagnostic and therapeutic methods have several disadvantages. We aim to develop more specific instruments for the clinician and more effective treatments for the patients.

Bladder Cancer (Per-Uno Malmström)

Prostate Cancer (Anna Bill-Axelson)

Prostate Cancer (Pär Stattin)

Kidney Cancer and Prostate Cancer (Michael Häggman)

Publications 2018-2019, Urology

  • Loeb, Stacy; Folkvaljon, Yasin; Bratt, Ola; Robinson, David et al.

    Defining Intermediate Risk Prostate Cancer Suitable for Active Surveillance

    Part of Journal of Urology, p. 292-299, 2019.

  • Arthur, Rhonda; Møller, Henrik; Garmo, Hans; Häggström, Christel et al.

    Serum glucose, triglycerides, and cholesterol in relation to prostate cancer death in the Swedish AMORIS study

    Part of Cancer Causes and Control, p. 195-206, 2019.

  • Thomsen, Frederik Birkebaek; Bosco, Cecilia; Garmo, Hans; Adolfsson, Jan et al.

    Anti-androgen monotherapy versus gonadotropin-releasing hormone agonists in men with advanced, non-metastatic prostate cancer: a register-based, observational study

    Part of Acta Oncologica, p. 110-118, 2019.

    Open access
  • Beckmann, Kerri; Garmo, Hans; Adolfsson, Jan; Bosco, Cecilia et al.

    Androgen Deprivation Therapies and Changes in Comorbidity: A Comparison of Gonadotropin-releasing Hormone Agonists and Antiandrogen Monotherapy as Primary Therapy in Men with High-risk Prostate Cancer

    Part of European Urology, p. 676-683, 2019.

  • Cazzaniga, Walter; Ventimiglia, Eugenio; Alfano, Massimo; Robinson, David et al.

    Mini Review on the Use of Clinical Cancer Registers for Prostate Cancer: The National Prostate Cancer Register (NPCR) of Sweden

    Part of FRONTIERS IN MEDICINE, 2019.

    Open access
  • Bill-Axelson, Anna; Holmberg, Lars; Garmo, Hans

    Radical Surgery or Watchful Waiting in Prostate Cancer Reply

    Part of New England Journal of Medicine, p. 1084-1084, 2019.

  • Cazzaniga, Walter; Garmo, Hans; Robinson, David; Holmberg, Lars et al.

    Mortality after radical prostatectomy in a matched contemporary cohort in Sweden compared to the Scandinavian Prostate Cancer Group 4 (SPCG-4) study

    Part of BJU International, p. 421-428, 2019.

  • Adamo, Hanibal; Hammarsten, Peter; Hägglöf, Christina; Scherdin, Tove Dahl et al.

    Prostate cancer induces C/EBP expression in surrounding epithelial cells which relates to tumor aggressiveness and patient outcome

    Part of The Prostate, p. 435-445, 2019.

  • Sverrisson, Ingvar; Folkvaljon, Folke; Chabok, Abbas; Stattin, Pär et al.

    Anastomotic leakage after anterior resection in patients with rectal cancer previously irradiated for prostate cancer

    Part of European Journal of Surgical Oncology, p. 341-346, 2019.

  • Ventimiglia, Eugenio; Van Hemelrijck, Mieke; Lindhagen, Lars; Stattin, Pär et al.

    How to measure temporal changes in care pathways for chronic diseases using health care registry data

    Part of BMC Medical Informatics and Decision Making, 2019.

    Open access
  • Häggström, Christel; Garmo, Hans; de Luna, Xavier; Van Hemelrijck, Mieke et al.

    Survival after radiotherapy versus radical cystectomy for primary muscle-invasive bladder cancer: A Swedish nationwide population-based cohort study

    Part of Cancer Medicine, p. 2196-2204, 2019.

    Open access
  • Lotan, Yair; Bivalacqua, Trinity J.; Downs, Tracy; Huang, William et al.

    Blue light flexible cystoscopy with hexaminolevulinate in non-muscle-invasive bladder cancer: review of the clinical evidence and consensus statement on optimal use in the USA - update 2018

    Part of Nature reviews. Urology, p. 377-386, 2019.

    Open access
  • Turker, Polat; Segersten, Ulrika; Malmström, Per-Uno; Hemdan, Tammer et al.

    Is Bcl-2 a predictive marker of neoadjuvant chemotherapy response in patients with urothelial bladder cancer undergoing radical cystectomy?

    Part of Scandinavian journal of urology, p. 45-50, 2019.

    Open access
  • Malmström, Per-Uno; Skaaheim, Erik; Boström, Peter J.; Gudjonsson, Sigidur et al.

    Progress towards a Nordic standard for the investigation of hematuria: 2019

    Part of Scandinavian journal of urology, p. 1-6, 2019.

    Open access
  • Beckmann, Kerri; Russell, Beth; Josephs, Debra; Garmo, Hans et al.

    Chronic inflammatory diseases, anti-inflammatory medications and risk of prostate cancer: a population-based case-control study

    Part of BMC Cancer, 2019.

    Open access
  • Trinquart, Ludovic; Bill-Axelson, Anna; Rider, Jennifer R.

    Restricted Mean Survival Times to Improve Communication of Evidence from Cancer Randomized Trials and Observational Studies

    Part of European Urology, p. 137-139, 2019.

  • Robinson, David; Garmo, Hans; Van Hemelrijck, Mieke; Damber, Jan-Erik et al.

    Androgen deprivation therapy for prostate cancer and risk of dementia

    Part of BJU International, p. 87-92, 2019.

    Open access
  • Crawley, Danielle; Chamberlain, Florence; Garmo, Hans; Rudman, Sarah et al.

    A systematic review of the literature exploring the interplay between prostate cancer and type two diabetes mellitus

    Part of ecancermedicalscience, 2018.

    Open access
  • Robinson, David; Garmo, Hans; Lissbrant, Ingela Franck; Widmark, Anders et al.

    Prostate Cancer Death After Radiotherapy or Radical Prostatectomy: A Nationwide Population-based Observational Study

    Part of European Urology, p. 502-511, 2018.

    Open access
  • Gnanapragasam, V. J.; Bratt, O.; Muir, K.; Lees, L. S. et al.

    The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study

    Part of BMC Medicine, 2018.

    Open access
  • van Kessel, Kim E. M.; van der Keur, Kirstin A.; Dyrskjot, Lars; Algaba, Ferran et al.

    Molecular Markers Increase Precision of the European Association of Urology Non-Muscle-Invasive Bladder Cancer Progression Risk Groups

    Part of Clinical Cancer Research, p. 1586-1593, 2018.

  • Russell, Beth; Garmo, Hans; Beckmann, Kerri; Stattin, Pär et al.

    A case-control study of lower urinary-tract infections, associated antibiotics and the risk of developing prostate cancer using PCBaSe 3.0

    Part of PLoS ONE, 2018.

    Open access
  • Tomic, Katarina; Ventimiglia, Eugenio; Robinson, David; Häggström, Christel et al.

    Socioeconomic status and diagnosis, treatment, and mortality in men with prostate cancer. Nationwide population-based study

    Part of International Journal of Cancer, p. 2478-2484, 2018.

  • Winerdal, Malin E.; Krantz, David; Hartana, Ciputra A.; Zirakzadeh, Ali A. et al.

    Urinary Bladder Cancer Tregs Suppress MMP2 and Potentially Regulate Invasiveness

    Part of CANCER IMMUNOLOGY RESEARCH, p. 528 528-538 538, 2018.

  • Holfeld, Aleš; Valdés, Alberto; Malmström, Per-Uno; Segersten, Ulrika et al.

    Parallel Proteomic Workflow for Mass Spectrometric Analysis of Tissue Samples Preserved by Different Methods

    Part of Analytical Chemistry, p. 5841-5849, 2018.

  • Humanistiska teatern, Engelska parken, Uppsala 2018-09-07 09:00

    Lycken, Magdalena

    Living and dying with prostate cancer: Population-based register studies

    Open access
  • Van Hemelrijck, Mieke; Ulmer, Hanno; Nagel, Gabriele; Peter, Raphael Simon et al.

    Longitudinal study of body mass index, dyslipidemia, hyperglycemia, and hypertension in 60,000 men and women in Sweden and Austria

    Part of PLoS ONE, 2018.

    Open access
  • FitzGerald, L. M.; Zhao, S.; Leonardson, A.; Geybels, M. S. et al.

    Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases

    Part of Prostate Cancer and Prostatic Diseases, p. 228-237, 2018.

    Open access
  • Crawley, Danielle; Garmo, Hans; Rudman, Sarah; Stattin, Pär et al.

    Does a prostate cancer diagnosis affect management of pre-existing diabetes? Results from PCBaSe Sweden: a nationwide cohort study

    Part of BMJ Open, 2018.

    Open access
  • Hartana, C. A.; Bergman, E. Ahlen; Broome, A.; Berglund, S. et al.

    Tissue-resident memory T cells are epigenetically cytotoxic with signs of exhaustion in human urinary bladder cancer

    Part of Clinical and Experimental Immunology, p. 39-53, 2018.

    Open access
  • Häggström, Christel; Van Hemelrijck, Mieke; Garmo, Hans; Robinson, David et al.

    Heterogeneity in risk of prostate cancer: A Swedish population-based cohort study of competing risks and Type 2 diabetes mellitus

    Part of International Journal of Cancer, p. 1868-1875, 2018.

    Open access
  • Bergman, Emma Ahlen; Hartana, Ciputra Adijaya; Johansson, Markus; Linton, Ludvig B. et al.

    Increased CD4(+) T cell lineage commitment determined by CpG methylation correlates with better prognosis in urinary bladder cancer patients

    Part of Clinical Epigenetics, 2018.

    Open access
  • Kinsella, Netty; Stattin, Pär; Cahill, Declan; Brown, Christian et al.

    Factors Influencing Men's Choice of and Adherence to Active Surveillance for Low-risk Prostate Cancer: A Mixed-method Systematic Review

    Part of European Urology, p. 261-280, 2018.

  • Crawley, Danielle; Garmo, Hans; Rudman, Sarah; Stattin, Pär et al.

    Association between type 2 diabetes, curative treatment and survival in men with intermediate- and high-risk localized prostate cancer.

    Part of BJU International, p. 209-216, 2018.

  • Arthur, R.; Williams, R.; Garmo, Hans; Holmberg, Lars et al.

    Serum inflammatory markers in relation to prostate cancer severity and death in the Swedish AMORIS study

    Part of International Journal of Cancer, p. 2254-2262, 2018.

  • Bosco, Cecilia; Wong, Chloe; Garmo, Hans; Crawley, Danielle et al.

    Drugs for metabolic conditions and prostate cancer death in men on GnRH agonists.

    Part of BJU International, p. 260-267, 2018.

  • Stattin, Pär

    Quality Indicators For Global Benchmarking Of Localized Prostate Cancer Management Editorial Comment

    Part of Journal of Urology, p. 325-326, 2018.

  • Stattin, Pär; Sandin, Fredrik; Loeb, Stacy; Robinson, David et al.

    Public online reporting from a nationwide population-based clinical prostate cancer register

    Part of BJU International, p. 8-10, 2018.

    Open access
  • Palou, J.; Pisano, F.; Sylvester, R.; Joniau, S. et al.

    Recurrence, progression and cancer-specific mortality according to stage at re-TUR in T1G3 bladder cancer patients treated with BCG: not as bad as previously thought

    Part of World journal of urology, p. 1621-1627, 2018.

  • Watts, Eleanor L.; Appleby, Paul N.; Perez-Cornago, Aurora; Bueno-de-Mesquita, H. Bas et al.

    Low Free Testosterone and Prostate Cancer Risk: A Collaborative Analysis of 20 Prospective Studies

    Part of European Urology, p. 585-594, 2018.

    Open access
  • Pettersson, A.; Robinson, D.; Garmo, Hans; Holmberg, Lars et al.

    Reply to the letter to the editor 'Age at diagnosis and prognosis among prostate cancer patients treated with radiotherapy: evidenced from three independent cohort studies' by X. Dong, G. Ma and F. Chen

    Part of Annals of Oncology, p. 2020-2021, 2018.

  • Lissbrant, Ingela Franck; Ventimiglia, Eugenio; Robinson, David; Törnblom, Magnus et al.

    Nationwide population-based study on the use of novel antiandrogens in men with prostate cancer in Sweden

    Part of Scandinavian journal of urology, p. 143-150, 2018.

    Open access
  • Zare, Reza; Grabe, Magnus; Hermann, Gregers G.; Malmström, Per-Uno et al.

    Can routine outpatient follow-up of patients with bladder cancer be improved?: A multicenter prospective observational assessment of blue light flexible cystoscopy and fulguration

    Part of Research and Reports in Urology, p. 151-157, 2018.

    Open access
  • Soria, Francesco; Pisano, Francesca; Gontero, Paolo; Palou, J. et al.

    Predictors of oncological outcomes in T1G3 patients treated with BCG who undergo radical cystectomy

    Part of World journal of urology, p. 1775-1781, 2018.

  • Teleka, Stanley; Häggström, Christel; Nagel, Gabriele; Bjorge, Tone et al.

    Risk of bladder cancer by disease severity in relation to metabolic factors and smoking: A prospective pooled cohort study of 800,000 men and women

    Part of International Journal of Cancer, p. 3071-3082, 2018.

  • Perez-Cornago, Aurora; Appleby, Paul N.; Boeing, Heiner; Gil, Leire et al.

    Circulating isoflavone and lignan concentrations and prostate cancer risk: a meta-analysis of individual participant data from seven prospective studies including 2,828 cases and 5,593 controls

    Part of International Journal of Cancer, p. 2677-2686, 2018.

    Open access
  • Al-Mashhadi, Ammar; Häggman, Michael; Läckgren, Göran; Ladjevardi, Sam et al.

    Changes of arterial pressure following relief of obstruction in adults with hydronephrosis

    Part of Upsala Journal of Medical Sciences, p. 216-224, 2018.

    Open access
  • Hemdan, Tammer; Turker, Polat; Malmström, Per-Uno; Segersten, Ulrika et al.

    Choline-phosphate cytidylyltransferase-alpha as a possible predictor of survival and response to cisplatin neoadjuvant chemotherapy in urothelial cancer of the bladder

    Part of Scandinavian journal of urology, p. 200-205, 2018.

    Open access
  • Sjostrom, Carin; Thorstenson, Andreas; Strock, Viveka; Hosseini-Aliabad, Abolfazl et al.

    Treatment according to guidelines may bridge the gender gap in outcome for patients with stage T1 urinary bladder cancer

    Part of Scandinavian journal of urology, p. 186-193, 2018.

  • Bill-Axelson, Anna; Holmberg, Lars; Garmo, Hans; Taari, Kimmo et al.

    Radical Prostatectomy or Watchful Waiting in Prostate Cancer: 29-Year Follow-up

    Part of New England Journal of Medicine, p. 2319-2329, 2018.

  • Nugin, Hampus; Folkvaljon, Yasin; Damber, Jan-Erik; Adolfsson, Jan et al.

    Work-up and treatment of prostate cancer before and after publication of the first national guidelines on prostate cancer care in Sweden

    Part of Scandinavian journal of urology, p. 277-284, 2018.

  • Krantz, David; Hartana, Ciputra Adijaya; Winerdal, Malin E.; Johansson, Markus et al.

    Neoadjuvant Chemotherapy Reinforces Antitumour T cell Response in Urothelial Urinary Bladder Cancer

    Part of European Urology, p. 688-692, 2018.

  • Li, Weiqiang; Middha, Mridu; Bicak, Mesude; Sjoberg, Daniel D. et al.

    Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival

    Part of European Urology, p. 710-719, 2018.

  • Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

    U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

    Part of Acta Oncologica, p. 187-194, 2018.

    Open access
  • Acosta Ruiz, Vanessa; Ladjevardi, Sam; Brekkan, Einar; Häggman, Michael et al.

    Periprocedural outcome after laparoscopic partial nephrectomy versus radiofrequency ablation for T1 renal tumors:: A modified R.E.N.A.L nephrometry score adjusted comparison.

    Part of Acta Radiologica, p. 260-268, 2018.

  • Stranne, J.; Brasso, K.; Brennhovd, B.; Johansson, Eva et al.

    SPCG-15: a prospective randomized study comparing primary radical prostatectomy and primary radiotherapy plus androgen deprivation therapy for locally advanced prostate cancer

    Part of Scandinavian journal of urology, p. 313-320, 2018.

  • Danielsson, Gun; Malmström, Per-Uno; Jahnson, Staffan; Wijkström, Hans et al.

    Bladder health in patients treated with BCG instillations for T1G2-G3 bladder cancer - a follow-up five years after the start of treatment

    Part of Scandinavian journal of urology, p. 377-384, 2018.

  • Johansson, Eva; Steineck, Gunnar; Holmberg, Lars; Johansson, Jan-Erik et al.

    Quality of Life after Radical Prostatectomy or Watchful Waiting With or Without Androgen Deprivation Therapy: The SPCG-4 Randomized Trial

    Part of European Association of Urology, p. 134 134-142 142, 2018.

  • Jansson, Fredrik; Drevin, Linda; Frisell, Thomas; Stattin, Pär et al.

    Concordance of Non-Low-Risk Disease Among Pairs of Brothers With Prostate Cancer

    Part of Journal of Clinical Oncology, p. 1847-1852, 2018.

  • Sahlén, Klara; Dahlman, Pär; Brekkan, Einar; Lönnemark, Maria et al.

    Predictive value of secondary signs of obstruction in follow-up computed tomography of ureteral stones: a study with dynamic computed tomography

    Part of Scandinavian journal of urology, p. 59-64, 2018.

  • Pettersson, A; Robinson, D; Garmo, H; Holmberg, Lars et al.

    Age at diagnosis and prostate cancer treatment and prognosis: a population-based cohort study

    Part of Annals of Oncology, p. 377-385, 2018.

  • Assel, Melissa; Dahlin, Anders; Ulmert, David; Bergh, Anders et al.

    Association Between Lead Time and Prostate Cancer Grade: Evidence of Grade Progression from Long-term Follow-up of Large Population-based Cohorts Not Subject to Prostate-specific Antigen Screening

    Part of European Urology, p. 961-967, 2018.

  • Ventimiglia, Eugenio; Folkvaljon, Yasin; Carlsson, Stefan; Bratt, Ola et al.

    Nationwide, population-based study of post radical prostatectomy urinary incontinence correction surgery

    Part of Journal of Surgical Oncology, p. 321-327, 2018.

    Open access
  • Bergengren, Oskar; Garmo, Hans; Bratt, Ola; Holmberg, Lars et al.

    Satisfaction with Care Among Men with Localised Prostate Cancer: A Nationwide Population-based Study

    Part of European Urology Oncology, p. 37 37-45 45, 2018.

  • Jansson, Fredrik; Drevin, Linda; Frisell, Thomas; Stattin, Pär et al.

    Concordance of Non-Low-Risk Disease Among Pairs of Brothers With Prostate Cancer

    Part of Journal of Clinical Oncology, p. 1847-+, 2018.