Pain treatment using invasive nerve stimulation techniques

The possibility to treat chronic pain with implantable devices for nerve stimulation has existed for over 50 years. Yet, the treatment options have vastly increased the last decennium through the development of new wave-forms, improved implants, as well as new anatomical stimulation targets. However, several meta-analysis concluded that the evidence of the efficacy of theses therapies is insufficiently documented while the cost per patient is high. There is some understanding regarding the mechanisms of tonic stimulation at the level of the spinal cord, but very few human studies have explored the more recent high-frequency stimulation paradigms with the aim of identifying potential unique mechanistic aspects. The current knowledge is most often insufficient to guide the selection of therapy for a particular patient. In addition, data regarding the frequency of complications, long-term effects and cost-effectiveness in a Swedish or Nordic context are lacking. The overarching aim of our research is to fill some of these knowledge gaps and thus better match the individual patient, the pain state and the selected invasive nerve stimulation therapy.

Ongoing research projects and goals: 

  •      To benefit from multiple local and national quality registers to study and describe the effects of various invasive nerve-stimulation techniques for the treatment of chronic pain
  •      To study the effects of invasive stimulation devices in a controlled Nordic multicenter study

Contact person: Terje Kirketeig

Last modified: 2021-05-03